MaNaSu Foundation was started in 2006 by three brothers-Mr. Mannam Venkata Rayudu, the eldest, a Bangalore-based Electronics Engineer and Businessman, Dr. Gopicahand Mannam, a well-known cardiac surgeon and Managing Director, Star Hospitals, Hyderabad and also well-known for his philanthropic activities especially in the areas of Medical Care through Hrudaya Foundation and their younger cousin Dr. Mannam Chandra Mouli, a reputed journalist and book publisher and one of the leading team members of TV 9 Telugu.